ApoE and Aging

Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. Kuller, L. H., Shemanski, L., Manolio, T., Haan, M., Fried, L., Bryan, N., Burke, G. L., Tracy, R., & Bhadelia, R. (1998).  Stroke29(2), 388398.

ApoE plasma levels and risk of cardiovascular mortality in old age. Mooijaart, S. P., Berbée, J. F., van Heemst, D., Havekes, L. M., de Craen, A. J., Slagboom, P. E., Rensen, P. C., & Westendorp, R. G. (2006).  PLoS medicine3(6), e176.

Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer’s pathology and APOE genotype. Simpson, J. E., Ince, P. G., Shaw, P. J., Heath, P. R., Raman, R., Garwood, C. J., Gelsthorpe, C., Baxter, L., Forster, G., Matthews, F. E., Brayne, C., Wharton, S. B., & MRC Cognitive Function and Ageing Neuropathology Study Group (2011).  Neurobiology of aging32(10), 17951807.

A reduced astrocyte response to β-amyloid plaques in the ageing brain associates with cognitive impairment. Mathur, R., Ince, P. G., Minett, T., Garwood, C. J., Shaw, P. J., Matthews, F. E., Brayne, C., Simpson, J. E., Wharton, S. B., & MRC Cognitive Function and Ageing Neuropathology Study Group (2015).  PloS one10(2).

Longitudinal and nonlinear relations of dietary and Serum cholesterol in midlife with cognitive decline: results from EMCOA study. An Y, Zhang X, Wang Y, Wang Y, Liu W, Wang T, Qin Z, Xiao R.  Mol Neurodegener. 2019 Dec 30;14(1):51.

Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain. Felsky D, Patrick E, Schneider JA, Mostafavi S, Gaiteri C, Patsopoulos N, Bennett DA, De Jager PL.  Mol Neurodegener. 2018 Jul 24;13(1):38.